Santi's Restaurante Mexicano Menu — Charleston & Mt. Pleasant, SC

Santi's serves the most authentic Mexican cuisine in the Charleston area. The welcoming atmosphere, upbeat friendly staff, and famously strong margaritas keep Charleston locals and visitors coming back to both of our South Carolina locations.

Authentic Mexican Favorites

Our menu is packed with authentic Mexican dishes made the traditional way — the real-deal flavors that have made Santi's a Lowcountry favorite.

Strong Margaritas

No visit to Santi's is complete without one of our strong margaritas — one of the many reasons guests keep coming back.

Two Locations

Charleston: 1303 Meeting St, Charleston, SC — open 11 AM to 10 PM, (843) 722-2633.
Mt. Pleasant: 1471 Ben Sawyer Blvd, Mt. Pleasant, SC — open 11 AM to 9 PM, (843) 388-3146.

Frequently Asked Questions

Where is Santi's Restaurante Mexicano located?

Santi's has two locations: 1303 Meeting St, Charleston, SC, (843) 722-2633; and 1471 Ben Sawyer Blvd, Mt. Pleasant, SC, (843) 388-3146.

What are Santi's hours?

The Charleston location is open 11 AM to 10 PM, and the Mt. Pleasant location is open 11 AM to 9 PM. Call ahead to confirm current hours.

Visit Santi's

Menu items and prices may change. Call or visit Santi's in Charleston or Mt. Pleasant for the current menu and today's specials.